Keratocystic Odontogenic Tumour : Current concepts , theory and presentation of 2 contrasting cases .
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چکیده
Odontogenic keratocyst (OKC) is a cyst of tooth origin with an aggressive clinical behavior including a high recurrence rate. It has been rechristened to Keratocystic odontogenic tumour (KCOT), as it better reflects its neoplastic nature. We report 2 contrasting cases of KCOT in association with impacted teeth and revisit the various treatment modalities used to tackle the aggressive nature and keep its recurrence at bay. Most promising being use of molecular biology to treat such tumours which could eventually reduce or eliminate the need for aggressive methods to manage the lesions.
منابع مشابه
Giant Keratocystic Odontogenic Tumor: Three Cases and a Literature Review
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متن کاملGiant Keratocystic Odontogenic Tumor: Three Cases and Literature Review
INTRODUCTION A keratocystic odontogenic tumor is a benign intra-bone mass originating from dental lamina or its residue. It represents 2-11% of jaw cysts, and has a slow but aggressive growth. The evaluation of molecular characteristics, immunohistochemistry, and genetic expression currently have no established classification regarding the evolution and pathophysiologic pattern of these lesions...
متن کاملKeratocystic odontogenic tumour: an experience in the Northeast of Brazil.
INTRODUCTION Keratocystic odontogenic tumours raise particular interest, because of their high recurrence rate and association with nevoid basal cell carcinoma syndrome. OBJECTIVE To analyze the clinical and histopathological features of all cases diagnosed as keratocystic odontogenic tumour in a Brazilian population. METHODS A total of 64 keratocystic odontogenic tumours, arising in forty-...
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تاریخ انتشار 2013